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- Certificate of completion
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- Hands-on training (Live)
Learn the fundamentals of Whole Genome Sequencing (WGS), from genome organization and sequencing technologies to quality control, read alignment, genome coverage, and basic variant discovery. This 15-day beginner-friendly course provides a practical understanding of the complete WGS analysis workflow.
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Learn at your own pace with recordings
Whole genome sequencing reads an organism’s entire DNA. This course explains, in plain language, how a DNA sample becomes genome data and how that data is analysed to find genetic variants.
You learn how sequencers work, read FASTQ files and quality scores, run FastQC and MultiQC, trim reads, align them to the reference genome with BWA-MEM2, measure depth and coverage, call SNPs and indels with GATK and read VCF files, ending with a beginner mini project.

Learn from experienced educators and practitioners through practical, career-focused bioinformatics training.
13 answers about this course
Yes. The course starts with the fundamentals of Whole Genome Sequencing and progressively introduces practical WGS data analysis.
No. Prior WGS experience is not required. Basic knowledge of biology and genetics is helpful.
No advanced programming knowledge is required. Basic Linux command-line concepts will be introduced during the training.
The training is 15 hours delivered over 15 days, with 1 hour of live training each day.
The course focuses on hands-on bioinformatics analysis using sequencing datasets and industry-relevant WGS tools.
You will work with GATK, BWA-MEM2, SAMtools, FastQC, MultiQC, SnpEff and IGV.
Yes. The course covers SNP and INDEL variant calling, filtering and downstream interpretation.
Yes. You will learn how to annotate genetic variants and understand their potential functional consequences using SnpEff.
The training includes practical WGS datasets so that you can practice the complete analysis workflow.
Yes. The final sessions include a hands-on WGS mini project covering the workflow from raw sequencing reads to variant interpretation.
Yes. Participants who successfully complete the training requirements will receive a Certificate of Completion.
Yes. Course materials, practical resources and relevant analysis files will be provided as part of the training.
You get full access to all course materials for 3 months from the date of enrollment.
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Hear from learners building practical skills with Bio Help Learning.
This training helped me develop practical skills in whole-genome sequencing analysis, from read quality control using FastQC and MultiQC to read trimming, genome alignment, coverage assessment, and variant calling. Working with a real public dataset helped me understand how different bioinformatics tools fit together in a complete analytical workflow. The hands-on activities strengthened my confidence in using command-line tools and interpreting genomic data. I particularly appreciated the practical approach and the opportunity to apply the concepts through a real project.
Yao Apélété Roland TOGLOUniversity of Lomé TogoWhole Genome Sequencing (WGS) Data Analysis TrainingI really enjoyed the course and found it very useful: it gave a clear and practical overview of the whole WGS workflow, from raw reads to a VCF, and the hands-on sessions helped a lot.
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